Sensing

✨ Sensing

Organisms across the tree of life have developed a variety of apparatuses and strategies to probe the environment around them. Each sense (vision, smell, touch, taste, etc) requires the transduction of an external stimulus into something that can be understood and processed by the brain to lead to a response such as a thought or behavior. For example, when the stimulus is a visual scene, photons from the scene are guided to photoreceptors. Upon absorbing the light energy, a molecule within the photoreceptor changes its shape (isomerises), ultimately opening up ion channels, thereby producing nerve impulses that are transmitted to the brain. 

Artificial sensors have much to learn from their biological counterparts, in terms of geometry, fluid mechanics, signal transduction and integration, and more. In our work, we aim to integrate these biological ideas to create new sensors for a variety of applications, from indoor air quality sensing to medical diagnoses.  

Contacts: Haritosh Patel, Jack Alvarenga, Anna Shneidman

 

 

 

 

Publications

2023

Brandt S, Pavlichenko I, Shneidman A V, Patel H, Tripp A, Wong TSB, Lazaro S, Thompson E, Maltz A, Storwick T, et al. Nonequilibrium sensing of volatile compounds using active and passive analyte delivery. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(31):e2303928120. doi:10.1073/pnas.2303928120
Brandt S, Pavlichenko I, Shneidman A V, Patel H, Tripp A, Wong TSB, Lazaro S, Thompson E, Maltz A, Storwick T, et al. Nonequilibrium sensing of volatile compounds using active and passive analyte delivery. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(31):e2303928120. doi:10.1073/pnas.2303928120

2022

Yao Y, Bennett RKA, Xu Y, Rather AM, Li S, Cheung TC, Bhanji A, Kreder MJ, Daniel D, Adera S, et al. Wettability-based ultrasensitive detection of amphiphiles through directed concentration at disordered regions in self-assembled monolayers. Proceedings of the National Academy of Sciences of the United States of America. 2022;119(43):e2211042119. doi:10.1073/pnas.2211042119
Yao Y, Bennett RKA, Xu Y, Rather AM, Li S, Cheung TC, Bhanji A, Kreder MJ, Daniel D, Adera S, et al. Wettability-based ultrasensitive detection of amphiphiles through directed concentration at disordered regions in self-assembled monolayers. Proceedings of the National Academy of Sciences of the United States of America. 2022;119(43):e2211042119. doi:10.1073/pnas.2211042119

In the News

Project Air launched!

We're excited to be testing our Sensory Nature-Inspired Fact Finder of Indoor Air (SNIFFIA) at Harvard's Center for Green Buildings, in collaboration with UNC and the Wyss Institute. Read more about it at HarvardCGBC and the Wyss Institute.
HZ_team